منابع مشابه
Small bowel transplantation.
After struggling for three decades, SBT is finally emerging as a clinical reality. To become the standard therapy for the treatment of end-stage intestinal failure, SBT must offer a better quality of life, fewer risks, and lower costs than home TPN. To achieve this standard, protocols must be refined to obtain lower rates of rejection and infection as well as more consistent graft function.
متن کاملSmall Bowel Transplantation
swing over the last five years thanks to the remarkable improvement of its outcome. This has been due mainly to the improvement of immunosuppressive protocols. The pioneers in SBT using animal models include Alex Carrel (1902, first transplantation of an intestinal segment in the dog) (1), Lillehei (1955, first orthotopic SBT in the dog) (2), and Monchik and Russel (1971, first model of SBT in ...
متن کاملCadaveric small bowel and small bowel-liver transplantation in humans.
Five patients had complete cadaveric small bowel transplants under FK506 immunosuppression, one as an isolated graft and the other 4 in continuity with a liver. Three were children and two were adults. The five patients are living 2-13 months posttransplantation with complete alimentation by the intestine. The typical postoperative course was stormy, with sluggish resumption of gastrointestinal...
متن کاملSmall bowel and liver/small bowel transplantation in children.
A clinical trial of intestinal transplantation was initiated at the University of Pittsburgh in May 1990. Eleven children received either a combined liver/small bowel graft (n = 8) or an isolated small bowel graft (n = 3). Induction as well as maintenance immunosuppression was with FK-506 and steroids. Four patients were male, and seven were female; the age range was 6 months to 10.2 years. The...
متن کاملSmall bowel transplantation in mice.
Since 1990, the development of tacrolimus-based immunosuppression and improved surgical techniques, the increased array of potent immunosuppressive medications, infection prophylaxis, and suitable patient selection helped improve actuarial graft and patient survival rates for all types of intestine transplantation. Patients with irreversible intestinal failure and complications of parenteral nu...
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ژورنال
عنوان ژورنال: Current Opinion in Organ Transplantation
سال: 2000
ISSN: 1087-2418
DOI: 10.1097/00075200-200009000-00019